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NeoFox: annotating neoantigen candidates with neoantigen features

2021; Oxford University Press; Volume: 37; Issue: 22 Linguagem: Inglês

10.1093/bioinformatics/btab344

1367-4811

Franziska Lang, Pablo Riesgo-Ferreiro, Martin Löwer, Uǧur Şahin, Barbara Schrörs,

Immunotherapy and Immune Responses

The detection and prediction of true neoantigens is of great importance for the field of cancer immunotherapy. Wesearched the literature for proposed neoantigen features and integrated them into a toolbox called NEOantigen Feature toolbOX (NeoFox). NeoFox is an easy-to-use Python package that enables the annotation of neoantigen candidates with 16 neoantigen features.NeoFox is freely available as an open source Python package released under the GNU General Public License (GPL) v3 license at https://github.com/TRON-Bioinformatics/neofox.Supplementary data are available at Bioinformatics online.