Portal de Periódicos da CAPES

Revisão Acesso aberto Produção Nacional Revisado por pares

BIBTEX RIS

Amazon-derived nutraceuticals: Promises to mitigate chronic inflammatory states and neuroinflammation

2021; Elsevier BV; Volume: 148; Linguagem: Inglês

10.1016/j.neuint.2021.105085

1872-9754

Charles Elias Assmann, Grazielle Castagna Cezimbra Weis, Jéssica Righi da Rosa, Beatriz da Silva Rosa Bonadiman, Audrei de Oliveira Alves, Maria Rosa Chitolina Schetinger, Euler Esteves Ribeiro, Vera Maria Morsch, Ivana Beatrice Mânica da Cruz,

Indigenous Health and Education

Nutraceuticals have been the focus of numerous research in recent years and accumulating data support their use for promoting some health benefits. Several nutraceuticals have been widely studied as supplements due to their functional properties ameliorating symptoms associated with neurological disorders, such as oxidative stress and chronic inflammatory states. This seems to be the case of some fruits and seeds from the Amazon Biome consumed since the pre-Columbian period that could have potential beneficial impact on the human nervous system. The beneficial activities of these food sources are possibly related to a large number of bioactive molecules including polyphenols, carotenoids, unsaturated fatty acids, vitamins, and trace elements. In this context, this review compiled the research on six Amazonian fruits and seeds species and some of the major nutraceuticals found in their composition, presenting brief mechanisms related to their protagonist action in improving inflammatory responses and neuroinflammation.