Revisão Acesso aberto Revisado por pares

Improved SARS-CoV-2 Mpro inhibitors based on feline antiviral drug GC376: Structural enhancements, increased solubility, and micellar studies

2021; Elsevier BV; Volume: 222; Linguagem: Inglês

10.1016/j.ejmech.2021.113584

ISSN

1768-3254

Autores

Wayne Vuong, Conrad Fischer, Muhammad Bashir Khan, Marco J. van Belkum, Tess Lamer, Kurtis D. Willoughby, Jimmy Lu, Elena Arutyunova, Michael Joyce, Holly A. Saffran, Justin Shields, Howard S. Young, James A. Nieman, D. Lorne Tyrrell, M. Joanne Lemieux, John C. Vederas,

Tópico(s)

SARS-CoV-2 and COVID-19 Research

Resumo

Replication of SARS-CoV-2, the coronavirus causing COVID-19, requires a main protease (M

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