Artigo Acesso aberto Revisado por pares

Effects of pre‐analytical procedures on blood biomarkers for Alzheimer's pathophysiology, glial activation, and neurodegeneration

2021; Elsevier BV; Volume: 13; Issue: 1 Linguagem: Inglês

10.1002/dad2.12168

ISSN

2352-8729

Autores

Nicholas J. Ashton, Marc Suárez‐Calvet, Thomas K. Karikari, Juan Lantero Rodrı́guez, Anniina Snellman, Mathias Sauer, Joel Simrén, Carolina Minguillón, Karine Fauria, Kaj Blennow, Henrik Zetterberg,

Tópico(s)

Statistical Methods in Clinical Trials

Resumo

We tested how tube types (ethylenediaminetetraacetic acid [EDTA], serum, lithium heparin [LiHep], and citrate) and freeze-thaw cycles affect levels of blood biomarkers for Alzheimer's disease (AD) pathophysiology, glial activation, and neuronal injury.

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