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Cardiac involvement in consecutive unselected hospitalized COVID-19 population: In-hospital evaluation and one-year follow-up

2021; Elsevier BV; Volume: 339; Linguagem: Inglês

10.1016/j.ijcard.2021.06.056

1874-1754

Viviana Maestrini, Lucia Ilaria Birtolo, Marco Francone, Gioacchino Galardo, Nicola Galea, Paolo Severino, Francesco Alessandri, Maria Chiara Colaiacomo, Giulia Cundari, Cristina Chimenti, Carlo Lavalle, Maria Rosa Ciardi, Paolo Palange, Alberto Deales, Gabriella d’Ettorre, Claudio Maria Mastroianni, Carlo Catalano, Franco Ruberto, Francesco Pugliese, Giulia d’Amati, Francesco Fedele, Massimo Mancone, Alida Albante, Araimo Morselli Fabio, Daniela Auricchio, Letizia D'Antoni, Giovanna Barletta, Federico Bilotta, Matteo Brisciani, Katia Bruno, Bucarelli Maria Clelia, Alessandro Cappannoli, Giancarlo Ceccarelli, Paola Celli, Stella Consolo, Consoli Giulia, Croce Claudia, Beatrice Crocitti, Letizia D'Antoni, De Lazzaro Francesco, De Lauri Daniela, De Rose Maria, Del Bianco Andrea, Di Bella Valerio, Di Sano Laura, Di Santo Carmela, Santi Francavilla, Giannetti Lorena, Giovanni Giordano, Stefano Ianni, Imperiale Carmela, Ilaria Maestrini, Magnanimi Eugenia, Chiara Manganelli, Federica Maldarelli, S. Martelli, Teresa Messina, Novelli Martina, Patrizia Pasculli, Pasqualitto Fabiola, Pattelli Elisa, Pecorari Filippo, Perrella Serena, Angelo Petroianni, Piazzolla Mario, Portieri Monica, Silvia Prosperi, R. Sebastian, Ratini Fabiola, Claudia Ricci, Romano Hilde, Anna Sabani, Pietro Santopietro, Guglielmo Tellan, Luca Titi, Tordiglione Paolo, Antonella Tosi, Trigilia Fausto, Verduci Noemi, Paola Vaccaro,

Mechanical Circulatory Support Devices

BackgroundCardiovascular disease (CVD) can occur in COVID-19 and has impact on clinical course. Data on CVD prevalence in hospitalized COVID-19 patients and sequelae in survivors is limited. Aim of this prospective study carried out on consecutive unselected COVID-19 population, was to assess: 1) CVD occurrence among hospitalized COVID-19 patients, 2) persistence or new onset of CVD at one-month and one-year follow-up.MethodsOver 30 days n = 152 COVID-19 patients underwent cardiovascular evaluation. Standard electrocardiogram (ECG), Troponin and echocardiography were integrated by further tests when indicated. Medical history, arterial blood gas, blood tests, chest computed tomography and treatment were recorded. CVD was defined as the occurrence of a new condition during the hospitalization for COVID-19. Survivors attended a one-month follow-up visit and a one-year telephone follow-up.ResultsForty-two patients (28%) experienced a wide spectrum of CVD with acute myocarditis being the most frequent. Death occurred in 32 patients (21%) and more frequently in patients who developed CVD (p = 0.032). After adjustment for confounders, CVD was independently associated with death occurrence. At one-month follow-up visit, 7 patients (9%) presented persistent or delayed CVD. At one-year telephone follow-up, 57 patients (48%) reported persistent symptoms.ConclusionCardiovascular evaluation in COVID-19 patients is crucial since the occurrence of CVD in hospitalized COVID-19 patients is common (28%), requires specific treatment and increases the risk of in-hospital mortality. Persistence or delayed presentation of CVD at 1-month (9%) and persistent symptoms at 1-year follow-up (48%) suggest the need for monitoring COVID-19 survivors.