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Machine learning based analysis of speech dimensions in functional oropharyngeal dysphagia

2021; Elsevier BV; Volume: 208; Linguagem: Inglês

10.1016/j.cmpb.2021.106248

1872-7565

Sebastián Roldán-Vasco, Andrés Orozco‐Duque, Juan Camilo Suárez-Escudero, Juan Rafael Orozco‐Arroyave,

Voice and Speech Disorders

• The evaluation of swallowing impairments (i.e. dysphagia) is made by invasive and examiner’s dependent methods. • The physiology of the swallowing process led us to hypothesize that dysphagia can be assessed by non-invasive methods such as speech recordings • Speech related dimensions have been few addressed systematically in patients with dysphagia. • We found potential biomarkers of functional dysphagia from different speech tasks. • Automatic analyses driven by machine learning based models were carried out to determine the most suitable speech dimensions for dysphagia screening purposes. Background and objective: The normal swallowing process requires a complex coordination of anatomical structures driven by sensory and cranial nerves. Alterations in such coordination cause swallowing malfunctions, namely dysphagia. The dysphagia screening methods are quite subjective and experience dependent. Bearing in mind that the swallowing process and speech production share some anatomical structures and mechanisms of neurological control, this work aims to evaluate the suitability of automatic speech processing and machine learning techniques for screening of functional dysphagia. Methods: Speech recordings were collected from 46 patients with functional oropharyngeal dysphagia produced by neurological causes, and 46 healthy controls. The dimensions of speech including phonation, articulation, and prosody were considered through different speech tasks. Specific features per dimension were extracted and analyzed using statistical tests. Machine learning models were applied per dimension via nested cross-validation. Hyperparameters were selected using the AUC - ROC as optimization criterion. Results: The Random Forest in the articulation related speech tasks retrieved the highest performance measures ( AUC = 0.86 ± 0.10 , sensitivity = 0.91 ± 0.12 ) for individual analysis of dimensions. In addition, the combination of speech dimensions with a voting ensemble improved the results, which suggests a contribution of information from different feature sets extracted from speech signals in dysphagia conditions. Conclusions: The proposed approach based on speech related models is suitable for the automatic discrimination between dysphagic and healthy individuals. These findings seem to have potential use in the screening of functional oropharyngeal dysphagia in a non-invasive and inexpensive way.