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IL-6 Receptor Antagonist Therapy for Patients Hospitalized for COVID-19

2021; American Medical Association; Volume: 326; Issue: 6 Linguagem: Inglês

10.1001/jama.2021.11121

1538-3598

Michael A. Matthay, Anne F. Luetkemeyer,

Long-Term Effects of COVID-19

The WHO Rapid Evidence Appraisal for COVID-19 Therapies (REACT) Working Group; Pere Domingo; Isabel Mur; Gracia María Mateo; Maria del Mar Gutierrez; Virginia Pomar; Natividad de Benito; Noemí Corbacho; Silvia Herrera; Lucia Millan; Jessica Muñoz; Jorge Malouf; Maria Ema Molas; Victor Asensi; Juan Pablo Horcajada; Vicente Estrada; Felix Gutierrez; Ferran Torres; Jose A Perez-Molina; Jesús Fortun; Luisa M Villar; Ulla Hohenthal; Harri Marttila; Tytti Vuorinen; Marika Nordberg; Mika Valtonen; Matthew J Frigault; Michael K Mansour; Naomi J Patel; Ana Fernandes; Liam Harvey; Andrea S Foulkes; Brian C Healy; Ruta Shah; Ana Maria Bensaci; Ann E. Woolley; Sarah Nikiforow; Nina Lin; Manish Sagar; Harry Shrager; David S. Huckins; Matthew Axelrod; Michael D Pincus; Jorge Fleisher; Jon Lampa; Piotr Nowak; Jan C. Vesterbacka; Johan Rasmuson; Paul Skorup; Helena Janols; Katarina F Niward; Katerina Chatzidionysiou; Hilmir Asgeirsson; Åsa Parke; Ola Blennow; Anna-Karin Svensson; Soo Aleman; Anders Sönnerborg; Jan-Inge Henter; Anna Carin Horne; Farah Al-Beidh; Derek Angus; Djillali Annane; Yaseen Arabi; Abigail Beane; Scott Berry; Zahra Bhimani; Marc Bonten; Charlotte Bradbury; Frank Brunkhorst; Meredith Buxton; Allen Cheng; Matt Cove; Menno De Jong; Lennie Derde; Lise Estcourt; Herman Goossens; Anthony Gordon; Cameron Green; Rashan Haniffa; Nao Ichihara; Francois Lamontagne; Patrick Lawler; Ed Litton; John Marshall; Colin McArthur; Daniel McAuley; Shay McGuinness; Bryan McVerry; Stephanie Montgommery; Paul Mouncey; Srinivas Murthy; Alistair Nichol; Rachael Parke; Jane Parker; Felipe Reyes; Kathryn Rowan; Hiroki Saito; Marlene Santos; Chris Seymour; Manu Shankar-Hari; Alexis Turgeon; Anne Turner; Wilma van Bentum-Puijk; Frank van de Veerdonk; Steve Webb; Ryan Zarychanski; J Kenneth Baillie; Richard Beasley; Nichola Cooper; Robert Fowler; James Galea; Thomas Hills; Andrew King; Susan Morpeth; Mihai Netea; Kayode Ogungbenro; Ville Pettila; Steve Tong; Tim Uyeki; Taryn Youngstein; Alisa Higgins; Elizabeth Lorenzi; Lindsay Berry; Carlos Salama; Ivan O. Rosas; Belén Ruiz-Antorán; Elena Muñez Rubio; Antonio Ramos Martínez; José Campos Esteban; Cristina Avendaño Solá; Reuven Pizov; Jesus Sanz Sanz; Francisco Abad-Santos; Azucena Bautista-Hernández; Lucio García-Fraile; Ana Barrios; Ángela Gutiérrez Liarte; Tamara Alonso Pérez; Sebastian C Rodríguez-García; Gina Mejía-Abril; Jose Carlos Prieto; Rafael Leon; VIVIANE C. VEIGA; PHILLIP SCHEINBERG; DANIELLE L.C. FARIAS; JOÃO G. PRATS; ALEXANDRE B. CAVALCANTI; FLAVIA R. MACHADO; REGIS G. ROSA; OTÁVIO BERWANGER; LUCIANO C.P. AZEVEDO; RENATO D. LOPES; LETICIA K. DOURADO; CLAUDIO G. CASTRO Jr. ; FERNANDO G. ZAMPIERI; ALVARO AVEZUM; THIAGO C. LISBOA; SALOMÓN S.O. ROJAS; JULIANA C. COELHO; RODRIGO T. LEITE; JULIO CESAR CARVALHO; LUIS E.C. ANDRADE; ALEX R. SANDES; MARIA CAROLINA T. PINTÃO ; SUELI V. SANTOS; THIAGO M.L. ALMEIDA; ANDRÉ N. COSTA; OTAVIO C.E. GEBARA; FLAVIO G.R. FREITAS; EDUARDO S. PACHECO; DAVID J.B. MACHADO; JOSIANE MARTIN; FABIO G. CONCEIÇÃO; SUELLEN R.R. SIQUEIRA; LUCAS P. DAMIANI; LUCIANA M. ISHIHARA; DANIEL SCHNEIDER; DENISE DE SOUZA; Olivier Hermine; Xavier Mariette; Pierre Louis Tharaux; Matthieu Resche Rigon; Raphael Porcher; Philippe Ravaud; Elie Azoulay; Jacques Cadranel; Joseph Emmerich; Muriel Fartoukh; Bertrand Guidet; Marc Humbert; Karine Lacombe; Matthieu Mahevas; Frédéric Pene; Valérie Pourchet-Martinez; Frédéric Schlemmer; Annick Tibi; Yazdan Yazdanpanah; Maxime Dougados; Serge Bureau; Peter W Horby; Martin J Landray; Kenneth J Baillie; Maya H Buch; Lucy C Chappell; Jeremy N Day; Saul N Faust; Richard Haynes; Thomas Jaki; Katie Jeffery; Edmund Juszczak; Wei Shen Lim; Marion Mafham ; Alan Montgomery; Andrew Mumford; Guy Thwaites; Adeeba Kamarulzaman; Sharifah Faridah Syed Omar; Sasheela Ponnampalavanar; Raja Iskandar Syah Raja Azwa; Pui Li Wong; Anjanna Kukreja; Hang Cheng Ong; Helmi Sulaiman; Sazali Basri; Rong Xiang Ng; Bushra Megat Johari; Reena Rajasuriar; Meng Li Chong; Malinee Neelamegam; Syed Mukhtar Syed Mansor; Nurul Syuhada Zulhaimi; Cheng Siang Lee; Frederick Altice; Christina Price; Maricar Malinis; Mohd Shahnaz Hasan; Chee Kuan Wong; Suresh Chidambaram; Nor Arisah Misnan; Alif Adlan Mohd Thabit; Benedict Sim; Farah Nadiah Bidin; Mohd Abd Hafiz Mohd Abd Rahim; Sujana Saravanamuttu; Wei Xuan Tuang; Yasmin Mohamed Gani; Suvintheran Thangavelu; Kim Heng Tay; Nur Munirah Ibrahim; Luqman Alhakim Halid; Kok Tong Tan; Mohd Noor Azreet Mukri; Masita Arip; Hui Moon Koh; Syarifah Nurul Ain Syed Badaruddin; Letchumi Raja Sureja; Geok Ying Chun; JULIAN TORRE-CISNEROS; NICOLAS MERCHANTE; RAFAEL LEON; SHEILA CARCEL; JOSE CARLOS GARRIDO; Eitan Galun; Alex Soriano; José Antonio Martínez; Clara Castán; Roger Paredes; David Dalmau; Cristina Carbonell; Gerard Espinosa; Pedro Castro; José Muñóz; Alex Almuedo; Sergio Prieto; Iván Pacheco; Mark Ratain; Jennifer Pisano; Mary Strek; Ayodeji Adegunsoye; Theodore Karrison; Declercq Jozefien; Van Damme Karel F.A.; De Leeuw Elisabeth; Bosteels Cedric; Maes Bastiaan; Manu Shankar-Hari, PhD, MSc; Claire L. Vale, PhD; Peter J. Godolphin, PhD; David Fisher, MSc; Julian P. T. Higgins, PhD; Francesca Spiga, PhD; Jelena Savović, PhD; Jayne Tierney, PhD; Gabriel Baron, PhD; Julie S. Benbenishty, PhD; Lindsay R. Berry, PhD; Niklas Broman, MD; Alexandre Biasi Cavalcanti, MD; Roos Colman, MSc; Stefanie L. De Buyser, PhD; Lennie P. G. Derde, MD, PhD; Pere Domingo, PhD; Sharifah Faridah Omar, MD; Ana Fernandez-Cruz, MD, PhD; Thijs Feuth, MD, PhD; Felipe Garcia, MD, PhD; Rosario Garcia-Vicuna, PhD; Isidoro Gonzalez-Alvaro, PhD; Anthony C. Gordon, MBBS, MD; Richard Haynes, DM; Olivier Hermine, MD, PhD; Peter W. Horby, MBBS; Nora K. Horick, MS; Kuldeep Kumar, MSc; Bart N. Lambrecht, MD, PhD; Martin J. Landray, PhD; Lorna Leal, MD, PhD; David J. Lederer, MD; Elizabeth Lorenzi, PhD; Xavier Mariette, MD, PhD; Nicolas Merchante, MD, PhD; Nor Arisah Misnan, MMed; Shalini V. Mohan, MD; Michael C. Nivens, PhD; Jarmo Oksi, MD, PhD; Jose A. Perez-Molina, PhD; Reuven Pizov, MD; Raphael Porcher, PhD; Simone Postma, MD; Reena Rajasuriar, PhD; Athimalaipet V. Ramanan, MD; Philippe Ravaud, MD, PhD; Pankti D. Reid, MD, MPH; Abraham Rutgers, MD, PhD; Aranzazu Sancho-Lopez, MD, PhD; Todd B. Seto, MD; Sumathi Sivapalasingam, MD; Arvinder Singh Soin, MS; Natalie Staplin, PhD; John H. Stone, MD, MPH; Garth W. Strohbehn, MD; Jonas Sunden-Cullberg, MD, PhD; Julian Torre-Cisneros, PhD; Larry W. Tsai, MD; Hubert van Hoogstraten, MD, PhD; Tom van Meerten, MD, PhD; Viviane Cordeiro Veiga, PhD; Peter E. Westerweel, MD, PhD; Srinivas Murthy, MD, CM, MHSc; Janet V. Diaz, MD; John C. Marshall, MD; Jonathan A. C. Sterne, PhD