
Dolutegravir-Based Antiretroviral Therapy for the Treatment of Patients Co-Infected with Tuberculosis and HIV: A Multicenter, Phase 3B, Noncomparative, Open-Label, Randomized Trial
2018; RELX Group (Netherlands); Linguagem: Inglês
10.2139/ssrn.3244943
ISSN1556-5068
AutoresKelly E. Dooley, Richard Kaplan, Noluthando Mwelase, Beatriz Grinsztejn, Eduardo Ticona, Marcus Lacerda, Omar Sued, Elena Belonosova, Mounir Ait‐Khaled, Konstantinos Angelis, Dannae Brown, Rajendra Singh, Christine L. Talarico, Allan R. Tenorio, Michael R. Keegan, Michael Aboud, INSPIRING Study Group,
Tópico(s)Pneumocystis jirovecii pneumonia detection and treatment
ResumoBackground: Concurrent treatment of tuberculosis and HIV is challenging owing to drug interactions, overlapping toxicities, and immune reconstitution inflammatory syndrome (IRIS). The efficacy and safety of dolutegravir were assessed in adults with HIV and drug-susceptible tuberculosis.
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