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Recreational drugs 25I-NBOH and 25I-NBOMe bind to both Sudlow's sites I and II of human serum albumin (HSA): biophysical and molecular modeling studies

2021; Royal Society of Chemistry; Volume: 45; Issue: 29 Linguagem: Inglês

10.1039/d1nj00806d

1369-9261

Wellington Alves de Barros, Marina de Magalhães Silva, Maria Dayanne de A. Dantas, Josué Carinhanha Caldas Santos, Isis Martins Figueiredo, Otávio Augusto Chaves, Carlos Maurício R. Sant’Anna, Ângelo de Fátima,

Drug Transport and Resistance Mechanisms

25I-NBOH and 25I-NBOMe simultaneously bind to sites I and II of HSA, which may affect their distribution and effects.