Produção Nacional
MicroRNAs: understanding their role in gene expression and cancer
2021; Instituto Israelita de Ensino e Pesquisa Albert Einstein; Volume: 19; Linguagem: Inglês
10.31744/einstein_journal/2021rb5996
ISSN2317-6385
AutoresAriany Lima Jorge, Erik Ribeiro Pereira, Christian Sousa de Oliveira, Eduardo dos Santos Ferreira, Edmara Toledo Ninzoli Menon, Susana Nogueira Diniz, Julia Alejandra Pezuk,
Tópico(s)Cancer-related molecular mechanisms research
ResumoMicroRNAs are small RNA molecules that regulate gene expression in cells. These small molecules comprise 17 to 25 nucleotides and are able to recognize target messenger RNAs by sequence complementarity and regulate their protein translation. Different microRNAs are expressed in all human cells. There is over 2,500 microRNAs described in humans that are involved in virtually all biological processes. Given their role as gene expression regulators, these molecules have been widely investigated and are thought to be associated with [...]
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