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Nanoparticles as a novel and promising antiviral platform in veterinary medicine

2021; Springer Science+Business Media; Volume: 166; Issue: 10 Linguagem: Inglês

10.1007/s00705-021-05177-w

1432-8798

Mohamed Fawzy, Gasser M. Khairy, Ahmed Hesham, Ali A. Rabaan, Ahmed G. El-Shamy, Abdou Nagy,

Immunotherapy and Immune Responses

Traditional veterinary virus vaccines, such as inactivated and live-attenuated vaccines, have achieved tremendous success in controlling many viral diseases of livestock and chickens worldwide. However, many recent viral outbreaks caused by different emerging and re-emerging viruses continue to be reported annually worldwide. It is therefore necessary to develop new control regimens. Nanoparticle research has received considerable attention in the last two decades as a promising platform with significant success in veterinary medicine, replacing traditional viral vector vaccines. However, the field of nanoparticle applications is still in its initial phase of growth. Here, we discuss various preparation methods, characteristics, physical properties, antiviral effects, and pharmacokinetics of well-developed nanoparticles and the potential of nanoparticles or nano-vaccines as a promising antiviral platform for veterinary medicine.