Artigo Acesso aberto Revisado por pares

SARS-CoV-2 Neutralization Resistance Mutations in Patient with HIV/AIDS, California, USA

2021; Centers for Disease Control and Prevention; Volume: 27; Issue: 10 Linguagem: Inglês

10.3201/eid2710.211461

ISSN

1080-6059

Autores

Seth A. Hoffman, Cristina Costales, Malaya K. Sahoo, Srikanth Palanisamy, Fumiko Yamamoto, ChunHong Huang, Michelle Verghese, Daniel Solis, Mamdouh Sibai, Aruna Subramanian, Lucy S. Tompkins, Philip Grant, Robert W. Shafer, Benjamin A. Pinsky,

Tópico(s)

SARS-CoV-2 detection and testing

Resumo

We report persistent severe acute respiratory syndrome coronavirus 2 infection in a patient with HIV/AIDS; the virus developed spike N terminal domain and receptor binding domain neutralization resistance mutations. Our findings suggest that immunocompromised patients can harbor emerging variants of severe acute respiratory syndrome coronavirus 2.

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