Artigo Revisado por pares

Long-Term Results and Complications of Intracavitary Bacillus Calmette-Guerin Therapy for Bladder Cancer

1984; Lippincott Williams & Wilkins; Volume: 132; Issue: 3 Linguagem: Inglês

10.1016/s0022-5347(17)49690-x

ISSN

1527-3792

Autores

Álvaro Morales,

Tópico(s)

Urological Disorders and Treatments

Resumo

No AccessJournal of Urology1 Sep 1984Long-Term Results and Complications of Intracavitary Bacillus Calmette-Guerin Therapy for Bladder Cancer Alvaro Morales Alvaro MoralesAlvaro Morales View All Author Informationhttps://doi.org/10.1016/S0022-5347(17)49690-XAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Clinical studies on intracavitary bacillus Calmette-Guerin therapy for bladder cancer have been conducted at this institution for more than 10 years. The 82 patients treated for prophylaxis of multiple superficial recurrences, residual tumors or carcinoma in situ have been followed for 2 to 7 years after treatment. The long-term results confirm previous studies showing the effectiveness of bacillus Calmette-Guerin in the prophylaxis and therapy of superficial vesical neoplasms. However, some decrease is observed in the population free of disease with a prolonged followup. Recent modifications in the original protocol have been introduced to enhance the effectiveness of the vaccine. Side effects during or shortly after treatment were minor and self-limiting in the large majority of patients (fever, bladder irritability and hematuria). Mild, transient hepatic dysfunction was noted in 2 patients. Hematological disturbances were insignificant. No patient had permanent structural or functional alterations of the bladder © 1984 by The American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetailsCited ByMcKiernan J, Holder D, Ghandour R, Barlow L, Ahn J, Kates M, Badalato G, Roychoudhury A, Decastro G and Benson M (2018) Phase II Trial of Intravesical Nanoparticle Albumin Bound Paclitaxel for the Treatment of Nonmuscle Invasive Urothelial Carcinoma of the Bladder after bacillus Calmette-Guérin Treatment FailureJournal of Urology, VOL. 192, NO. 6, (1633-1638), Online publication date: 1-Dec-2014.McKiernan J, Barlow L, Laudano M, Mann M, Petrylak D and Benson M (2018) A Phase I Trial of Intravesical Nanoparticle Albumin-Bound Paclitaxel in the Treatment of Bacillus Calmette-Guérin Refractory Nonmuscle Invasive Bladder CancerJournal of Urology, VOL. 186, NO. 2, (448-451), Online publication date: 1-Aug-2011.ALI-EL-DEIN B, NABEEH A, ISMAIL E and GHONEIM M (2018) SEQUENTIAL BACILLUS CALMETTE-GUERIN AND 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Volume 132Issue 3September 1984Page: 457-459 Advertisement Copyright & Permissions© 1984 by The American Urological Association Education and Research, Inc.MetricsAuthor Information Alvaro Morales More articles by this author Expand All Advertisement PDF DownloadLoading ...

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