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BIBTEX RIS

Rapid and Direct Photocatalytic C(sp 3 )−H Acylation and Arylation in Flow

2021; Wiley; Volume: 60; Issue: 39 Linguagem: Inglês

10.1002/anie.202108987

ISSN

1521-3773

Autores

Daniele Mazzarella, Antonio Pulcinella, Loïc Bovy, Rémy Broersma, Timothy Noël,

Tópico(s)

Catalytic Cross-Coupling Reactions

Resumo

Herein, we report a photocatalytic procedure that enables the acylation/arylation of unfunctionalized alkyl derivatives in flow. The method exploits the ability of the decatungstate anion to act as a hydrogen atom abstractor and produce nucleophilic carbon-centered radicals that are intercepted by a nickel catalyst to ultimately forge C(sp

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