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BIBTEX RIS

Characteristics of adult patients with chronic intestinal failure due to short bowel syndrome: An international multicenter survey

2021; Elsevier BV; Volume: 45; Linguagem: Inglês

10.1016/j.clnesp.2021.07.004

2405-4577

Loris Pironi, Ezra Steiger, Francisca Joly, Palle B. Jeppesen, Geert Wanten, Anna Simona Sasdelli, C. Chambrier, Umberto Aimasso, Manpreet S. Mundi, Kinga Szczepanek, Amelia Jukes, Miriam Theilla, Marek Kunecki, Joanne Daniels, Mireille J. Serlie, Florian Poullenot, Sheldon C. Cooper, Henrik Højgaard Rasmussen, Charlene Compher, David Seguy, Adriana Crivelli, Lidia Santarpia, Francesco William Guglielmi, Nada Rotovnik Kozjek, S. Schneider, Lars Ellegård, Ronan Thibault, Przemysław Matras, Konrad Matysiak, A. Van Gossum, Alastair Forbes, Nicola Wyer, Marina Taus, N. Virgili, Margie O’Callaghan, Brooke Chapman, Emma Osland, Cristina Cuerda, G. Udvarhelyi, Lynn Jones, André Dong Won Lee, Luisa Masconale, P. Orlandoni, Corrado Spaggiari, Marta Bueno, Maryana Doitchinova-Simeonova, Aurora E. Serralde‐Zúñiga, Gabriel Olveira, Željko Krznarić, László Czakó, Gintautas Kėkštas, Alejandro Sanz‐París, Ma Estrella Petrina Jáuregui, Ana Zugasti Murillo, Eszter Schäfer, Jann Arends, José Pablo Suárez Llanos, Nader N. Youssef, Giorgia Brillanti, Elena Nardi, Simon Lal, Adriana Crivelli, H. Solar Muñiz, Brooke Chapman, Lynn Jones, Margie O’Callaghan, Emma Osland, Ruth Hodgson, Siobhan Wallin, Kay Lasenby, A. Van Gossum, André Dong Won Lee, Maryana Doitchinova-Simeonova, Željko Krznarić, Henrik Højgaard Rasmussen, Chrisoffer Brandt, Palle B. Jeppesen, C. Chambrier, Francisca Joly, V. Boehm, J. Bataille, Lore Billiauws, Florian Poullenot, S. Schneider, David Seguy, Ronan Thibault, Jann Arends, László Czakó, T Molnár, Mihaly Zsilak-Urban, Ferenc Izbéki, Péter Sahin, G. Udvarhelyi, Eszter Schäfer, Miriam Theilla, Anna Simona Sasdelli, Giorgia Brillanti, Elena Nardi, Loris Pironi, Umberto Aimasso, Merlo F. Dario, Valentino Bertasi, Luisa Masconale, Francesco William Guglielmi, N. Regano, P. Orlandoni, Lidia Santarpia, Lucia Alfonsi, Corrado Spaggiari, Marina Taus, Debora Busni, Gintautas Kėkštas, Aurora E. Serralde‐Zúñiga, Lyn Gillanders, Marek Kunecki, Przemysław Matras, Konrad Matysiak, Kinga Szczepanek, Anna Zmarzły, Nada Rotovnik Kozjek, Marta Bueno, Cristina Cuerda, C Garde, N. Virgili, Gabriel Olveira, Ma Estrella Petrina Jáuregui, Alejandro Sanz‐París, José Pablo Suárez Llanos, Ana Zugasti Murillo, Lars Ellegård, Mireille J. Serlie, Cora Jonker, Geert Wanten, Sheldon C. Cooper, Joanne Daniels, Simona Di, Niamh Keane, Pinal S. Patel, Alastair Forbes, Sarah-Jane Hughes, Amelia Jukes, Rachel Lloyd, Simon Lal, Arun Abraham, G. Garside, Michael Taylor, Jian Wu, Trevor Smith, C. Pither, M Stroud, Nicola Wyer, R Parmar, Nicola Burch, Sarah Zeraschi, Charlene Compher, Manpreet S. Mundi, Denise Jezerski, Ezra Steiger, Elena Nardi, Giorgia Brillanti,

Intestinal Malrotation and Obstruction Disorders

Background and aims The case-mix of patients with intestinal failure due to short bowel syndrome (SBS-IF) can differ among centres and may also be affected by the timeframe of data collection. Therefore, the ESPEN international multicenter cross-sectional survey was analyzed to compare the characteristics of SBS-IF cohorts collected within the same timeframe in different countries. Methods The study included 1880 adult SBS-IF patients collected in 2015 by 65 centres from 22 countries. The demographic, nutritional, SBS type (end jejunostomy, SBS-J; jejuno-colic anastomosis, SBS-JC; jejunoileal anastomosis with an intact colon and ileocecal valve, SBS-JIC), underlying disease and intravenous supplementation (IVS) characteristics were analyzed. IVS was classified as fluid and electrolyte alone (FE) or parenteral nutrition admixture (PN). The mean daily IVS volume, calculated on a weekly basis, was categorized as 3 L/day. Results In the entire group: 60.7% were females and SBS-J comprised 60% of cases, while mesenteric ischaemia (MI) and Crohn’ disease (CD) were the main underlying diseases. IVS dependency was longer than 3 years in around 50% of cases; IVS was infused ≥5 days/week in 75% and FE in 10% of cases. Within the SBS-IF cohort: CD was twice and thrice more frequent in SBS-J than SBS-JC and SBS-JIC, respectively, while MI was more frequent in SBS-JC and SBS-JIC. Within countries: SBS-J represented 75% or more of patients in UK and Denmark and 50-60% in the other countries, except Poland where SBS-JC prevailed. CD was the main underlying disease in UK, USA, Denmark and The Netherlands, while MI prevailed in France, Italy and Poland. Conclusions SBS-IF type is primarily determined by the underlying disease, with significant variation between countries. These novel data will be useful for planning and managing both clinical activity and research studies on SBS.