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Tuberculosis Burden and Determinants of Treatment Outcomes According to Age in Brazil: A Nationwide Study of 896,314 Cases Reported Between 2010 and 2019

2021; Frontiers Media; Volume: 8; Linguagem: Inglês

10.3389/fmed.2021.706689

ISSN

2296-858X

Autores

Beatriz Barreto‐Duarte, Mariana Araújo‐Pereira, Betânia M. F. Nogueira, Luciana Fonseca Sobral, Moreno S. Rodrigues, Artur T. L. Queiroz, Michael S. Rocha, Vanessa Nascimento, Alexandra B. Souza, Marcelo Cordeiro‐Santos, Afrânio Lineu Kritski, Timothy R. Sterling, María B. Arriaga, Bruno B. Andrade,

Tópico(s)

Chronic Disease Management Strategies

Resumo

Approximately 1.4 million people die annually worldwide from tuberculosis. Large epidemiologic studies can identify determinants of unfavorable clinical outcomes according to age, which can guide public health policy implementation and clinical management to improve outcomes. We obtained data from the national tuberculosis case registry; data were reported to the Brazilian National Program (SINAN) between 2010 and 2019. Clinical and epidemiologic variables were compared between age groups (child: <10 years, young: 10-24years, adult: 25-64years, and elderly: ≥65years). Univariate comparisons were performed together with second-generation

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