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Oral Adult Rhabdomyoma

2021; Springer Science+Business Media; Volume: 15; Issue: 4 Linguagem: Inglês

10.1007/s12105-021-01371-z

1936-0568

Augusto César Leal da Silva Leonel, Stefanny Torres dos Santos, Elaine Judite de Amorim Carvalho, Jurema Freire Lisboa de Castro, Oslei Paes de Almeida, Danyel Elias da Cruz Pérez,

Oral and Maxillofacial Pathology

This report describes a case of an adult rhabdomyoma (ARM) occurring in the oral cavity. A 47-year-old man was referred for the diagnosis of a painless, well-circumscribed, submucous nodule located on the floor of the mouth, measuring approximately 6.0 cm in length. Computed tomography revealed a well-defined, solid, and hypodense mass. A benign salivary gland or mesenchymal tumor were the main diagnostic hypotheses. Under local anesthesia, the patient underwent surgical excision. Microscopically, the tumor comprised large polygonal well-defined cells with abundant, eosinophilic granular cytoplasm with cross striations. No atypia or mitosis was observed. The cells were positive for muscle-specific actin, desmin, and sarcomeric alpha-actin. Based on these features, a diagnosis of ARM was established. No recurrence was observed after 48 months. Although rare, ARM should be considered in the differential diagnosis of oral submucosal nodules, especially those located on the floor of the mouth.