Portal de Periódicos da CAPES

Propionibacterium acnes

2006; Oxford University Press; Volume: 42; Issue: 3 Linguagem: Inglês

10.1111/j.1472-765x.2006.01866.x

1472-765X

Amie Perry, Peter A. Lambert,

Acne and Rosacea Treatments and Effects

Propionibacterium acnes, a common skin organism, is most notably recognized for its role in acne vulgaris. It also causes postoperative and device-related infections and has been associated with a number of other conditions such as sarcoidosis and synovitis, acne, pustulosis, hyperostosis and osteitis (SAPHO), although its precise role as a causative agent remains to be determined. Propionibacterium acnes produces a number of virulence factors and is well known for its inflammatory and immunomodulatory properties. Recent publication of the P. acnes genome should provide further insights into the pathogenic capabilities of the organism and potentially lead to the development of new therapies.