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Specific visualization of tubulin-containing structures in tissue culture cells by immunofluorescence

1975; Elsevier BV; Volume: 95; Issue: 1 Linguagem: Inglês

10.1016/0014-4827(75)90615-1

1090-2422

K. Weber, Th. Bibring, Mary Osborn,

Protist diversity and phylogeny

Antibody against tubulin from the outer doublets of sea urchin sperm flagella reacts with tubulin-containing structures in mammalian cells. Thus cytoplasmic microtubules, vinblastine-induced paracrystals and the full spectrum of mitotic figures can be visualized by immunofluorescence. These results show that the tubulin structure has been highly conserved during evolution.