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The Lennox-Gastaut syndrome: a severe type of childhood epilepsy.

1968; National Institutes of Health; Volume: 24; Issue: 3 Linguagem: Inglês

E. Niedermeyer,

Pharmacological Effects and Toxicity Studies

The Lennox-Gastaut syndrome is characterized by a) severe convulsive disorder with various types of seizures, b) mental retardation, c) slow spike-wave complexes in the EEG, d) heterogeneous etiologies and variable pathological substrata, e) a very poor response to the usual anticonvulsive medication (with the possible exception of Diazepam (Valium)). The onset falls into infancy and childhood, rarely into adolescence. The occurrence of atonic-akinetic seizures and purely tonic attacks are helpful in establishing the diagnosis which should be corroborated by the EEG.