Halo nevi
1968; Wiley; Volume: 22; Issue: 1 Linguagem: Inglês
10.1002/1097-0142(196807)22
ISSN1097-0142
AutoresDonald M. Wayte, Elson B. Helwig,
Tópico(s)RNA regulation and disease
ResumoCancerVolume 22, Issue 1 p. 69-90 ArticleFree Access Halo nevi Donald M. Wayte Ramc, Donald M. Wayte Ramc Major Dermal Pathology Branch, Armed Forces Institute of Pathology, Washington, D.C. 20305Search for more papers by this authorElson B. Helwig MD, Corresponding Author Elson B. Helwig MD Dermal Pathology Branch, Armed Forces Institute of Pathology, Washington, D.C. 20305Armed Forces Institute of Pathology, Washington, D.C. 20305===Search for more papers by this author Donald M. Wayte Ramc, Donald M. Wayte Ramc Major Dermal Pathology Branch, Armed Forces Institute of Pathology, Washington, D.C. 20305Search for more papers by this authorElson B. Helwig MD, Corresponding Author Elson B. Helwig MD Dermal Pathology Branch, Armed Forces Institute of Pathology, Washington, D.C. 20305Armed Forces Institute of Pathology, Washington, D.C. 20305===Search for more papers by this author First published: July 1968 https://doi.org/10.1002/1097-0142(196807)22:1 3.0.CO;2-DCitations: 87AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onEmailFacebookTwitterLinkedInRedditWechat Abstract The clinicopathologic features of 108 halo nevi removed from 100 patients are presented, as well as a review of the previous reports on this subject. The term "halo nevus" is used to describe a pigmented nevus surrounded by a zone or margin of depigmented skin and having a life history that includes the centripetal extension of the depigmented halo and the spontaneous disappearance of the nevus. This process is most commonly found on the trunk of young Caucasian persons; it does not appear to be directly related to vitiligo but may be related to actinic radiation. The microscopic features consist of a nevus cell nevus, usually compound in type and infiltrated and surrounded by lymphocytes and histiocytes. The halo area has dopa-negative clear cells at all levels of the epidermis; electron microscopy has shown these to be Langerhans' cells. Differentiation of halo nevus from malignant melanoma and inflammatory dermatoses is presented. References 1 Allen, E. P.: Malignant melanoma, spontaneous regression after pregnancy. Brit. Med. 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