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State of Sweat: Emerging Wearable Systems for Real-Time, Noninvasive Sweat Sensing and Analytics

2021; American Chemical Society; Volume: 6; Issue: 8 Linguagem: Inglês

10.1021/acssensors.1c01133

2379-3694

Roozbeh Ghaffari, Da Som Yang, Joohee Kim, Amer Mansour, John A. Wright, Jeffrey B. Model, Donald E. Wright, John A. Rogers, Tyler R. Ray,

Non-Invasive Vital Sign Monitoring

Skin-interfaced wearable systems with integrated colorimetric assays, microfluidic channels, and electrochemical sensors offer powerful capabilities for noninvasive, real-time sweat analysis. This Perspective details recent progress in the development and translation of novel wearable sensors for personalized assessment of sweat dynamics and biomarkers, with precise sampling and real-time analysis. Sensor accuracy, system ruggedness, and large-scale deployment in remote environments represent key opportunity areas, enabling broad deployment in the context of field studies, clinical trials, and recent commercialization. On-body measurements in these contexts show good agreement compared to conventional laboratory-based sweat analysis approaches. These device demonstrations highlight the utility of biochemical sensing platforms for personalized assessment of performance, wellness, and health across a broad range of applications.