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PD62-04 TENSILE STRENGTH OF PENILE TUNICA ALBUGINEA IN A PRIMATE MODEL

2021; Lippincott Williams & Wilkins; Volume: 206; Issue: Supplement 3 Linguagem: Inglês

10.1097/ju.0000000000002099.04

1527-3792

Alexander M. Kandabarow, Eric Chuang, Kevin E. McKenna, Brian Le, Kevin T. McVary, Alberto Colombo,

Sexual Differentiation and Disorders

You have accessJournal of UrologySexual Function/Dysfunction: Basic Research & Pathophysiology (PD62)1 Sep 2021PD62-04 TENSILE STRENGTH OF PENILE TUNICA ALBUGINEA IN A PRIMATE MODEL Alexander M. Kandabarow, Eric Chuang, Kevin McKenna, Brian Le, Kevin McVary, and Alberto Colombo Alexander M. KandabarowAlexander M. Kandabarow More articles by this author , Eric ChuangEric Chuang More articles by this author , Kevin McKennaKevin McKenna More articles by this author , Brian LeBrian Le More articles by this author , Kevin McVaryKevin McVary More articles by this author , and Alberto ColomboAlberto Colombo More articles by this author View All Author Informationhttps://doi.org/10.1097/JU.0000000000002099.04AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract INTRODUCTION AND OBJECTIVE: The penis is fundamentally a biomechanical implement. Penile load-bearing is assumed by the tunica albuginea, a sheet of collagenous tissue enveloping the corpora cavernosa. Quantifying the tunica’s biomechanical properties is essential for understanding erectile dysfunction and safe functioning of penile prostheses. These quantities have been directly measured in human cadavers and cingulates but never in fresh primate specimens. METHODS: We procured penile tissue from freshly sacrificed male baboons (Papio anubis). To generate experimental samples, strips of tunica were prepared in both longitudinal and circumferential orientations. To calculate the elasticity and failure strength of a sample, we generated a stress-strain curve via mechanical extensometry. From this curve the Young’s modulus and ultimate tensile strength were calculated. RESULTS: Fifteen samples from six penes produced a mean Young’s modulus of 26.4 MPa (SD 10.0) longitudinally (n=9) and 11.9 MPa (SD 4.2) circumferentially (n=6). The mean ultimate tensile strength was 3.8 MPa (SD 1.6) longitudinally and 1.9 MPa (SD 0.4 MPa) circumferentially. These values show tunica albuginea has a similar elasticity and failure strength to cartilage. CONCLUSIONS: These first measures of the biomechanical properties of fresh primate penile tunica albuginea will be compared to fresh human tissues and applied to computational models. Source of Funding: None © 2021 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 206Issue Supplement 3September 2021Page: e1073-e1073 Advertisement Copyright & Permissions© 2021 by American Urological Association Education and Research, Inc.MetricsAuthor Information Alexander M. Kandabarow More articles by this author Eric Chuang More articles by this author Kevin McKenna More articles by this author Brian Le More articles by this author Kevin McVary More articles by this author Alberto Colombo More articles by this author Expand All Advertisement Loading ...