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BIBTEX RIS

The HIV protease inhibitor, ritonavir, corrects diverse brain phenotypes across development in mouse model of DYT-TOR1A dystonia

2021; American Association for the Advancement of Science; Volume: 13; Issue: 607 Linguagem: Inglês

10.1126/scitranslmed.abd3904

ISSN

1946-6242

Autores

Zachary F. Caffall, Bradley J. Wilkes, Ricardo Hernández, Joseph E. Rittiner, Jennifer T. Fox, Kanny K. Wan, Miranda K. Shipman, Steven A. Titus, Yaqin Zhang, Samarjit Patnaik, Matthew D. Hall, Matthew B. Boxer, Min Shen, Zhuyin Li, David E. Vaillancourt, Nicole Calakos,

Tópico(s)

Parkinson's Disease Mechanisms and Treatments

Resumo

Ritonavir, identified by a DYT1 dystonia in vitro drug screen, corrects neuronal firing response and white matter deficits in the DYT1 mouse brain.

Referência(s)