Portal de Periódicos da CAPES

Etiological and epidemiological features of acute respiratory infections in China

2021; Nature Portfolio; Volume: 12; Issue: 1 Linguagem: Inglês

10.1038/s41467-021-25120-6

2041-1723

Zhongjie Li, Xiao‐Ai Zhang, Xiang Ren, Qing‐Bin Lu, Xiang Ren, Cuihong Zhang, Yifei Wang, Sheng-Hong Lin, Xiao‐Ai Zhang, Jun Li, Shiwen Zhao, Zhigang Yi, Xiao Chen, Zuosen Yang, Lei Meng, Xinhua Wang, Yingle Liu, Xin Wang, Ai‐Li Cui, Shengjie Lai, Tao Jiang, Yang Yuan, Lusha Shi, Meng-Yang Liu, Yuliang Zhu, Anran Zhang, Zhijie Zhang, Yang Yang, Michael P. Ward, Luzhao Feng, Huaiqi Jing, Liuyu Huang, Wenbo Xu, Yu Chen, Jianguo Wu, Zhenghong Yuan, Mengfeng Li, Yu Wang, Liping Wang, Li‐Qun Fang, Wei Liu, Simon I Hay, George F. Gao, Weizhong Yang, Weizhong Yang, George F. Gao, Zhongjie Li, Liping Wang, Xiang Ren, Yifei Wang, Sheng-Hong Lin, Cuihong Zhang, Mengjie Geng, Xin Wang, Huaiqi Jing, Wenbo Xu, Ai‐Li Cui, Yujuan Shen, Yanyan Jiang, Qiao Sun, Lipeng Hao, Chuchu Ye, Wei Liu, Xiao‐Ai Zhang, Liuyu Huang, Yong Wang, Wei Zhang, Qi Zhang, Weiyong Liu, Ziyong Sun, Fa-Xian Zhan, Ying Xiong, Deshan Yu, Chun-Xiang Wang, Shengcang Zhao, Wenrui Wang, Xia Lei, Juansheng Li, Yuhong Wang, Yan Zhang, Jun-Peng Yang, Yanbo Wang, Fu-Cai Quan, Xiong Zhi-jun, Liping Liang, Quan-E Chang, Yun Wang, Ping Wang, Lingling Mao, Jiameng Li, Likun Lv, Jun Xu, Chang Shu, Xiao Chen, Yu Chen, Yanjun Zhang, Lunbiao Cui, Kuicheng Zheng, Xingguo Zhang, Xi Zhang, Lihong Tu, Wei Wang, Xiaofang Zhou, Xiaofang Pei, Tianli Zheng, Xiao-Ni Zhong, Qin Li, Hua Ling, Ding-Ming Wang, Shijun Li, Shu-Sen He, Xun Zhu, Changwen Ke, Hong Xiao, Biao Di, Ying Zhang, Hongwei Zhou, Nan Yu, Hongjian Li, Fang Yang, Fuxiang Wang, Jun Wang,

Influenza Virus Research Studies

Nationwide prospective surveillance of all-age patients with acute respiratory infections was conducted in China between 2009‒2019. Here we report the etiological and epidemiological features of the 231,107 eligible patients enrolled in this analysis. Children <5 years old and school-age children have the highest viral positivity rate (46.9%) and bacterial positivity rate (30.9%). Influenza virus, respiratory syncytial virus and human rhinovirus are the three leading viral pathogens with proportions of 28.5%, 16.8% and 16.7%, and Streptococcus pneumoniae, Mycoplasma pneumoniae and Klebsiella pneumoniae are the three leading bacterial pathogens (29.9%, 18.6% and 15.8%). Negative interactions between viruses and positive interactions between viral and bacterial pathogens are common. A Join-Point analysis reveals the age-specific positivity rate and how this varied for individual pathogens. These data indicate that differential priorities for diagnosis, prevention and control should be highlighted in terms of acute respiratory tract infection patients' demography, geographic locations and season of illness in China.