Portal de Periódicos da CAPES

MOLLUSCICIDAL STEROIDAL SAPONINS FROM YUCCA ELEPHANTIPES

2001; Volume: 10; Issue: 1 Linguagem: Inglês

10.21608/zjps.2001.181595

2356-9786

Mortada El-Sayed, Hanan El-Nahas,

Natural product bioactivities and synthesis

Three spirostanol and two furostanol saponins have been isolated from the methanol extract of the leaves of Yucca elephantipes .The structures of these saponins were established as 3-O-β -D-xylopyranosyl-(1→2)- B-D- glucopyranosyl-(1→3)- β-D-glucopyranoside D- galactopyranoside yamogenin (I),3-O-β-D-xylopyranosyl-(1-→2)[ -β-D- glucopyranosyl-( 1-3 )] , 26-B-D- glucopyranoside (25 S) -furost- 5-ene-3,22,26 -triol (II), 3- O- α -L -rhamnopyranosyl- ( 1→2 )-[ β- D-xylopyranosyl- (1-→3) -β-D-glucopyranosyl-(1–>4)- β-D-galactopyranoside gitogenin (III), 3-O-β-D-xylopyranosyl- ( 1→ 3)- [β-D-glucopyranosyl -(1→2) - s-D-glucopyranosyl-(1→4)- β- D-galactopyranoside gitogenin (IV),and 26-0-β-D-glucopyranosyl-22-0-methyl (25R)-5-furostan -2,3,26-tetrol-3-O-[α-L-rhamnopyranosyl -(1->3)]- s -D-glucopyranosyl -(1->2)- β-D-glucopyranosyl-(1-4)- β-D- galactopyranoside (V). Saponins I, III and IV showed high molluscicidal activities against Biomphalaria alexandrina snails after 24 hours exposure (LC90 = 4,9 and 7 ppm ) whereas saponins II and V were inactive up to 50 ppm