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Similar Antibody Responses Against Severe Acute Respiratory Syndrome Coronavirus 2 in Individuals Living Without and With Human Immunodeficiency Virus on Antiretroviral Therapy During the First South African Infection Wave

2021; Oxford University Press; Volume: 75; Issue: 1 Linguagem: Inglês

10.1093/cid/ciab758

1537-6591

Jumari Snyman, Shi Hsia Hwa, Robert Krause, Daniel Muema, Tarylee Reddy, Yashica Ganga, Farina Karim, Alasdair Leslie, Alex Sigal, Thumbi Ndung’u, Moherndran Archary, Kaylesh J Dullabh, Philip Goulder, Guy Harling, Rohen Harrichandparsad, Kobus Herbst, Prakash Jeena, Thandeka Khoza, Nigel Klein, Henrik N. Kløverpris, Rajhmun Madansein, Mohlopheni J. Marakalala, Matilda Mazibuko, Mosa Moshabela, Ntombifuthi Mthabela, Kimesh Naidoo, Zaza M. Ndhlovu, Kennedy Nyamande, Nesri Padayatchi, Vinod Patel, Theresa Smit, Adrie J. C. Steyn, Emily Wong,

COVID-19 epidemiological studies

There is limited understanding of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pathogenesis in African populations with a high burden of infectious disease comorbidities such as human immunodeficiency virus (HIV). The kinetics, magnitude, and duration of virus-specific antibodies and B-cell responses in people living with HIV (PLWH) in sub-Saharan Africa have not been fully characterized.