Produção Nacional
Revisado por pares
Effect of bioactive glasses containing strontium and potassium on dentin permeability
2021; Wiley; Volume: 110; Issue: 3 Linguagem: Inglês
10.1002/jbm.b.34931
ISSN1552-4981
AutoresLuisa Alegria Acevedo, Letícia Antonelo Campos, Iolanda Cristina Justus Dechandt, Gustavo Alegria, Renato Luiz Siqueira, Edgar D. Zanotto, Francisco Carlos Serbena, Fábio André dos Santos,
Tópico(s)Temporomandibular Joint Disorders
ResumoAbstract Dentin hypersensitivity (DH) is characterized by pain caused by an external stimulus on exposed dentin. Different therapeutic approaches have been proposed to mitigate this problem; however, none of them provide permanent pain relief. In this study, we synthesized and characterized experimental bioactive glasses containing 3.07 mol% SrO or 3.36 mol% K 2 O (both equivalent to 5 wt% in the glass), and evaluated their effect on dentin permeability to verify their potential to treat DH. The experimental materials were characterized by field‐emission scanning electron microscopy, Fourier transform infrared spectroscopy, micro‐Raman spectroscopy, and X‐ray diffraction to confirm the respective structures and chemical compositions. The reduction in the hydraulic conductance of dentin was evaluated at the three stages: minimum permeability; maximum permeability (24% ethylenediaminetetraacetic acid [EDTA] treatment); and final dentin permeability after treatment with the bioactive glasses. They all promoted a reduction in dentin permeability, with a significant difference for each sample and posttreatment group. Also, a significant reduction in dentin permeability was observed even after a simulated toothbrushing test, demonstrating effective action of these materials against DH. Besides, incorporating 3.07 mol% SrO was a positive factor. Therefore, strontium's desensitizing and re‐mineralizing properties can be further exploited in bioactive glasses to promote a synergistic effect to treat DH.
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