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CHARACTERIZATION OF THE US INFERTILITY PATIENT JOURNEY: EVALUATION OF REAL-WORLD DATA FROM US ASSISTED REPRODUCTIVE TECHNOLOGY (ART) CENTERS

2021; Elsevier BV; Volume: 116; Issue: 3 Linguagem: Inglês

10.1016/j.fertnstert.2021.07.481

1556-5653

Patrick W. Heiser, Howard D. Taske,

Ovarian function and disorders

Describe the utilization of different infertility treatments based upon patient age, observed efficacy, and geodemographic data. Deidentified data inclusive of age, intervention, number of treatment cycles, pregnancy outcome, and PRIZM geo-demographic data was collected from 15 different US centers with 89 office locations from 2015-2019. The analysis included 182,544 intrauterine insemination (IUI) and assisted reproductive technology (ART) treatment cycles from 58,799 infertility patients. Only patients with ≥12 months of available treatment history were included; the possibility that patients sought treatment at centers outside of this analysis during the period of evaluation cannot be excluded. The percentage of patients undergoing IUI only was highest in patients 42 years underwent IUI only with cumulative efficacy of 6% after 3.1 cycles. On average, 58.1% of all subjects who underwent IUI-only failed to become pregnant. Conversely, older patients were more likely to undergo ART-only. Roughly 19% of subjects independent of age advanced from IUI to ART treatment cycles. [Table] Patients in states with insurance mandates tended to undergo more treatment cycles with greater progression from IUI to IVF dependent on the strength of the mandate.Tabled 1TABLE % (n/N)Age (yrs)IUI onlyIUI only, failed (subset)IUI & ARTART only 4217.1 (559/3278)88.2 (493/559)15.2 (497/3278)67.8 (2222/3278)ALL32.2 (18938/58799)58.1 (11010/18938)19.4 (11404/58799)48.4 (28456/58799) Open table in a new tab Patient age, observed efficacy, and geodemographic factors inclusive of insurance mandates impact the treatment of the infertility patient.