Produção Nacional
Revisado por pares
Does the Combined Effect of Resistance Training with EPO and Iron Sulfate Improve Iron Metabolism in Older Individuals with End-Stage Renal Disease?
2021; Multidisciplinary Digital Publishing Institute; Volume: 13; Issue: 9 Linguagem: Inglês
10.3390/nu13093250
ISSN2072-6643
AutoresHugo de Luca Corrêa, Víctor M. Alfaro‐Magallanes, Sting Ray Gouveia Moura, Rodrigo Vanerson Passos Neves, Lysleine Alves Deus, Fernando Sousa Honorato, Victor Lopes Silva, Artur Temizio Oppelt Raab, Beatriz Maia, Isabela Akaishi Padula, Lucas Santos de Gusmão Alves, Rafaela Araújo Machado, Andrea Lucena Reis, Jonato Prestes, Carlos Ernesto Santos Ferreira, Luiz Sinésio Silva Neto, Fernanda Silveira Tavares, Rosângela Vieira de Andrade, Thiago dos Santos Rosa,
Tópico(s)Body Composition Measurement Techniques
ResumoWe sought to investigate the effects of resistance training (RT) combined with erythropoietin (EPO) and iron sulfate on the hemoglobin, hepcidin, ferritin, iron status, and inflammatory profile in older individuals with end-stage renal disease (ESRD). ESRD patients (n: 157; age: 66.8 ± 3.6; body mass: 73 ± 15; body mass index: 27 ± 3), were assigned to control (CTL; n: 76) and exercise groups (RT; n: 81). The CTL group was divided according to the iron treatment received: without iron treatment (CTL—none; n = 19), treated only with iron sulfate or EPO (CTL—EPO or IRON; n = 19), and treated with both iron sulfate and EPO (CTL—EPO + IRON; n = 76). The RT group followed the same pattern: (RT—none; n = 20), (RT—EPO or IRON; n = 18), and (RT—EPO + IRON; n = 86). RT consisted of 24 weeks/3 days per week at moderate intensity of full-body resistance exercises prior to the hemodialysis section. The RT group, regardless of the iron treatment, improved iron metabolism in older individuals with ESRD. These results provide some clues on the effects of RT and its combination with EPO and iron sulfate in this population, highlighting RT as an important coadjutant in ESRD-iron deficiency.
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