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1117P Mutational landscape of large cell neuroendocrine lung carcinoma: Molecular characterization using next generation sequencing

2021; Elsevier BV; Volume: 32; Linguagem: Inglês

10.1016/j.annonc.2021.08.199

1569-8041

María San Román, L. Sanz-Gómez, J. Chamorro-Pérez, Y. Lage, M.E. Olmedo García, Ana Gómez, E. Corral de la Fuente, Diana Isabel Rosero-Rodríguez, V. Albarrán Fernandez, Javier Pozas, P. Alvarez-Ballesteros, Elena Vida-Navas, J.J. Soto Castillo, Javier Torres-Jiménez, Jorge Esteban-Villarrubia, Inmaculada Orejana-Martín, Amparo Benito Berlinches, Pilar Garrido,

Glycosylation and Glycoproteins Research

Large cell neuroendocrine lung carcinoma (LCNEC) is an aggressive subtype with an incidence around 3% of all lung cancer. The treatment approach for advanced patients remains controversial due to the lack of large randomized trials including this subtype. Owing to this fact, molecular characterization using next generation sequencing (NGS) technology has become a key tool for the molecular profiling of LCNEC.