Produção Nacional
Revisado por pares
Characterization, Bioactivity and Application of Chitosan-Based Nanoparticles in a Food Emulsion Model
2021; Multidisciplinary Digital Publishing Institute; Volume: 13; Issue: 19 Linguagem: Inglês
10.3390/polym13193331
ISSN2073-4360
AutoresKarina Oliveira Lima, Cristian Mauricio Barreto Pinilla, Ailén Alemán, M.E. López‐Caballero, M.C. Gómez‐Guillén, P. Montero, Carlos Prentice,
Tópico(s)Proteins in Food Systems
ResumoIn this study, chitosan nanoparticles (CNPs) were prepared by the ionic gelation technique with tripolyphosphate (TPP), and the effect of CNP composition and physicochemical characteristics were evaluated. After the synthesis optimization, CNPs were used as carriers for a fish protein hydrolysate (FPH) with bioactive properties (CNPH). The physicochemical characteristics, antioxidant capacity and antimicrobial, antihypertensive and emulsifier properties of unloaded and loaded CNPs in a food system model were studied. CNPH showed a uniform particle distribution, size ~200 nm, high stability (zeta potential around 30 mV), radical scavenging activity and increased antimicrobial activity against Staphylococcus aureus, Shigella sonnei and Aeromonas hydrophila. Additionally, CNPH showed an angiotensin I-converting enzyme (ACE)-inhibitory activity of 63.6% and, when added to a food emulsion model, this system containing CNPs, with or without FHP, exhibited improved food emulsion stability. Thus, CNPs were able to carry the FPH while maintaining their bioactive properties and can be an alternative to the delivery of bioactive peptides with potential as an emulsion stabilizer for food applications.
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