Artigo Acesso aberto Revisado por pares

1376O The effect of hyperthermic intraperitoneal chemotherapy (HIPEC) upon cytoreductive surgery (CRS) in gastric cancer (GC) with synchronous peritoneal metastasis (PM): A randomized multicentre phase III trial (GASTRIPEC-I-trial)

2021; Elsevier BV; Volume: 32; Linguagem: Inglês

10.1016/j.annonc.2021.08.1485

ISSN

1569-8041

Autores

Beate Rau, Hauke Lang, Alfred Königsrainer, Ines Gockel, H. Rau, Hendrik Seeliger, Christian Lerchenmüller, Daniel Reim, Roger Wahba, Martin K. Angele, Steffen Heeg, Tobias Keck, Arved Weimann, Sascha Topp, P. Piso, Andreas Brandl, Evelyn Trips, Volker Heinemann, P. Thuss-Patience,

Tópico(s)

Gastrointestinal Tumor Research and Treatment

Resumo

In patients (pts) with PM from GC, palliative chemotherapy (CTx) is the treatment of choice. CRS and HIPEC is still matter of debate, as the evidence is controversial. We conducted a randomized controlled multicentre trial to explore the impact of HIPEC after CRS on overall survival (OS). (Funding German Cancer Aid; ClinicalTrials.gov, number NCT02158988).

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