Artigo Acesso aberto Produção Nacional Revisado por pares

The genome of the zoonotic malaria parasite Plasmodium simium reveals adaptations to host switching

2021; BioMed Central; Volume: 19; Issue: 1 Linguagem: Inglês

10.1186/s12915-021-01139-5

ISSN

1741-7007

Autores

Tobias Mourier, Denise Anete Madureira de Alvarenga, Abhinav Kaushik, Anielle de Pina-Costa, Olga Douvropoulou, Qingtian Guan, Francisco J. Guzmán‐Vega, Sarah Forrester, Filipe Vieira Santos de Abreu, Cesare Bianco Júnior, Júlio César de Souza, Sílvia Bahadian Moreira, Zelinda Maria Braga Hirano, Alcides Pissinatti, Maria de Fátima Ferreira‐da‐Cruz, Ricardo Lourenço‐de‐Oliveira, Stefan T. Arold, Daniel Jeffares, Patrícia Brasil, Cristiana Ferreira Alves de Brito, Richard Culleton, Cláudio Tadeu Daniel‐Ribeiro, Arnab Pain,

Tópico(s)

Insect symbiosis and bacterial influences

Resumo

Plasmodium simium, a malaria parasite of non-human primates (NHP), was recently shown to cause zoonotic infections in humans in Brazil. We sequenced the P. simium genome to investigate its evolutionary history and to identify any genetic adaptions that may underlie the ability of this parasite to switch between host species.

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