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BIBTEX RIS

Pharmacological and Therapeutic Potential of Myristicin: A Literature Review

2021; Multidisciplinary Digital Publishing Institute; Volume: 26; Issue: 19 Linguagem: Inglês

10.3390/molecules26195914

1433-1373

Elisa Frederico Seneme, Daiane Carla dos Santos, Evelyn Marcela Rodrigues Silva, Yollanda Edwirges Moreira Franco, Giovanna Barbarini Longato,

Traditional and Medicinal Uses of Annonaceae

Natural products have been used by humanity for many centuries to treat various illnesses and with the advancement of technology, it became possible to isolate the substances responsible for the beneficial effects of these products, as well as to understand their mechanisms. In this context, myristicin, a substance of natural origin, has shown several promising activities in a large number of in vitro and in vivo studies carried out. This molecule is found in plants such as nutmeg, parsley, carrots, peppers, and several species endemic to the Asian continent. The purpose of this review article is to discuss data published in the last 10 years at Pubmed, Lilacs and Scielo databases, reporting beneficial effects, toxicity and promising data of myristicin for its future use in medicine. From 94 articles found in the literature, 68 were included. Exclusion criteria took into account articles whose tested extracts did not have myristicin as one of the major compounds.