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INFECÇÃO POR COVID-19 EM PACIENTES TRANSPLANTADOS DE FÍGADO

2021; Volume: 24; Issue: 3 Linguagem: Inglês

10.53855/bjt.v24i3.418

2764-1589

Elodie Bomfim Hyppólito, Beatriz Hyppolito da Justa, Karen Soares Mendes, Thaís Azevedo Souza Fontenele, Júlia do Carmo Barroso, Isabela Carvalho Studart, Lívia Caronne, Antônio Haroldo Araújo Filho, Karla Brandão Pereira, Tarciso Daniel dos Santos da Rocha, Cynthia Viana Ferreira Gomes, Clébia Azevedo, Heloisa Vidal Alves Pereira, B.A. Feitosa Neto, Lêda Fátima Rocha Miranda, Gustavo Coelho, Denissa Ferreira Gomes Mesquita, Paulo Ewerton Garcia, Amaury de Castro e Silva Filho, Roberto da Justa Pires Neto, Evelyne Santana Girão, José Huygens Parente Garcia,

Long-Term Effects of COVID-19

SARS-Cov-2 (Covid-19) infection is a new clinical condition that has had a profound impact on the entire health system in the world, causing a significant reduction in the performance of organ transplants. The natural history of Covid-19 in liver transplant recipients is unknown. Purpose: To assess clinical manifestations, liver involvement, access to the healthcare system, and mortality of SARS-COV-2 infection (COVID-19) in liver transplanted patients at HUWC-UFC. Methods: We retrospectively assessed in a cross-sectional, observational study a series of 58 suspected cases of COVID-19 in liver transplanted patients at HUWC- UFC. Of these, 18 cases were confirmed to be SARS-CoV-2-infected. Results: The epidemiological profile of this series was that 13 individuals were male, with average age of 58.8 years (Δ35 to 75 years), mean liver transplantation time of 5 years (Δ0.5 to 11 years). All patients in this case series had some comorbidity, with diabetes, overweight and SAH being the most frequent. Most of these patients were treated in a hospital setting, but not all had access to chest tomography, RT-PCR for SARS-CoV-2 or intensive care when necessary. Of the 18 patients, 5 patients died due to coronavirus complications, the majority due to respiratory failure, resulting in a lethality rate of 27.8%. Conclusion: We conclude that Covid-19 infection had high lethality in liver transplanted patients at HUWC-UFC.