Portal de Periódicos da CAPES

OP05.08: Cardiac cycle timing parameters in fetuses with right ventricle outflow tract obstruction

2021; Wiley; Volume: 58; Issue: S1 Linguagem: Inglês

10.1002/uog.23969

1469-0705

Gelfman Laura, I. Soveral, L. Nogué, M. Pérez‐Cruz, M. Bennásar, M. Escobar, J. Martı́nez, María Dolores Gómez‐Roig, E. Gratacós, F. Crispi, O. Gómez,

Pregnancy and preeclampsia studies

The aim of this study was to investigate the differences in cardiac filling (FTF) and ejection time (ETF) fractions between fetuses with right ventricle tract obstruction, including pulmonary stenosis (PS) and tetralogy of Fallot with pulmonary stenosis (ToF-PS) and healthy fetuses. A total of 13 fetuses with PS and 34 with ToF-PS matched by gestational age (GA) at scan with 94 healthy fetuses; were included in the study. A comprehensive echocardiography was performed including the evaluation of biventricular FTF (defined as filling time/cardiac cycle time)*100 and ETF (defined as ejection time/cycle time)*100. Z-scores were calculated and compared among the three populations using an Anova test. The mean GA at echocardiography was 33.1 ± 3.07weeks with no differences between the three groups (p = 0.449). Our results showed that ToF-PS-fetuses presented a more prolonged right and left FTF (1.42 ± 1.75 vs0.40 ± 1.38; 1.35 ± 1.65 vs0,41 ± 1.16) compared to the control group with also a longer right ETF (1.99 ± 4.72 vs 0.49 ± 1.25). Conversely, fetuses with PS only showed a longer left ETF compared to healthy fetuses (2.04 ± 2.56 vs0.52 ± 1.28) (figure 1). Fetuses with ToF-PS presented a more prolonged biventricular FTF with a longer right ETF while fetuses with PS only showed a prolonged left EFT. These findings could be explained by a intracardiac shunt at different level, through the interventricular septal defect in fetuses with ToF-PS and at the level of the fossa ovale in the case of PS. More studies are needed to correlate these parameters with other echocardiographic measurements and to study their clinical applicability. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.