Portal de Periódicos da CAPES

Artigo Produção Nacional

BIBTEX RIS

Immediate effects of a real moderate interval-running training session on inflammatory profile

2020; Elsevier BV; Volume: 133; Linguagem: Inglês

10.1016/j.cyto.2020.155150

1096-0023

Ana Paula da Silva Azevedo, Clara Nóbrega, Joanna D.C.C. Lima, Emídio Marques de Matos‐Neto, Alberto Carlos Amadio, Marília Seelaender, Júlio Cerca Serrão,

Muscle metabolism and nutrition

• Moderate IRT session did not increased inflammatory profile. • Inflammatory modulation in running seems to be dose-dependent. • Inflammatory modulation may also be affected by energetic metabolism. • Relevant evidence for training planning and injuries or syndromes prevention. The study investigated the immediate effect of a moderate interval-running training session on circulating inflammatory cytokines concentration at real conditions of training. Nine recreational runners (5 women and 4 men; 68,33 ± 10,20 kg; 1,65 ± 0,07 m; 28,67 ± 4,24 years) had blood samples collected from antecubital vein before and immediately after a moderate interval-running training session without fasting. Cytokine levels were obtained from blood samples through Multiplex Analysis of Sample Protein Content, performed by Magpix® instrument. The assay detected the cytokines and calculated the plasma cytokine concentrations. Reduced concentration was observed after training session for all cytokines (p < 0.05), except for IP-10. Moderate effect sizes were identified in IL-6, IL-8, TNF-α, IP-10, MCP1 and GM-CSF. In summary, a single moderate interval-running training session at real conditions of training seems not to be stressing enough to increase cytokine levels as a response to the exercise. Results reinforce that immediate biochemical response and inflammatory modulation related to exercise is dose-dependent and may be influenced by other variables.