Glomerulopatia colapsante
2012; Q16635223; Volume: 140; Issue: 10 Linguagem: Inglês
10.4067/s0034-98872012001000016
ISSN0717-6163
AutoresJuan Carlos Said, Luz María Letelier S, Alejandro González, Cristóbal Escobillana, R Pisano,
Tópico(s)Pregnancy and Medication Impact
ResumoCollapsing glomerulopathyCollapsing glomerulopathy is a cause of nephrotic syndrome with massive proteinuria secondary to podocyte proliferation and glomerular collapse.It is characterized by an almost inevitable progression to end stage renal failure, poor response to treatment and high post-transplant recurrence.Its frequency has increased in recent years due to its common association with Human Immunodeficiency Virus (HIV) infection and the growing recognition of new etiologic agents such as drugs and parvovirus B19.Therefore, it is a disease of growing interest for clinicians.The aim of this review is to update the clinical presentation, diagnosis, pathogenesis and therapeutic alternatives of this disease.
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