Portal de Periódicos da CAPES

COVID-19 in vaccinated adult patients with hematological malignancies: preliminary results from EPICOVIDEHA

2021; Elsevier BV; Volume: 139; Issue: 10 Linguagem: Inglês

10.1182/blood.2021014124

1528-0020

Livio Pagano, Jon Salmanton‐García, Francesco Marchesi, Alberto López‐García, Sylvain Lamure, Federico Itri, María Gomes da Silva, Giulia Dragonetti, Iker Falces‐Romero, Jaap A. van Doesum, Uluhan Sili, Jorge Labrador, María Calbacho, Yavuz M. Bilgin, Barbora Weinbergerová, Laura Rubio i Serrano, José-María Ribera-Santa Susana, Sandra Malak, José Loureiro-Amigo, Andreas Glenthøj, Raúl Córdoba, Raquel Nunes Rodrigues, Tomás José González‐López, Linda Karlsson, María-Josefa Jiménez-Lorenzo, José‐Ángel Hernández‐Rivas, Ozren Jakšić, Zdeněk Ráčil, Alessandro Busca, Paolo Corradini, Martin Hoenigl, Н Н Климко, Philipp Koehler, Antonio Pagliuca, Francesco Passamonti, Oliver A. Cornely,

COVID-19 Clinical Research Studies

In a Plenary Paper, Mittelman and colleagues assess the relative clinical efficacy of mRNA vaccination on COVID-19 disease incidence and outcomes in patients with hematologic malignancies compared with healthy matched controls. This population-based study from Israel links prior observations of poor serologic responses to vaccination to higher risk for breakthrough infection, hospitalization, and death in patients with blood cancer, especially those on active antineoplastic therapy. In an accompanying Letter to Blood, Pagano et al provide supportive data using a multination survey approach to capture outcomes for COVID-19 in vaccinated patients with hematologic neoplasms. They also emphasize the higher risk among patients with lymphoid malignancies. Together, these findings argue for both continued deployment of booster programs and ongoing public health guidance for this vulnerable group.