Produção Nacional
Revisado por pares
Synthetic peptides as promising antiviral molecules
2021; Future Medicine; Volume: 17; Issue: 1 Linguagem: Inglês
10.2217/fvl-2021-0193
ISSN1746-0808
Autores Tópico(s)Respiratory viral infections research
ResumoFuture VirologyVol. 17, No. 1 EditorialSynthetic peptides as promising antiviral moleculesPedro FN SouzaPedro FN Souza *Author for correspondence: Tel.: +55 85 3366 9823; E-mail Address: pedrofilhobio@gmail.comhttps://orcid.org/0000-0003-2524-4434Collaborating Professor of Biochemistry & Molecular Biology Graduate Program at The Department of Biochemistry & Molecular Biology, Federal University of CearáPublished Online:12 Nov 2021https://doi.org/10.2217/fvl-2021-0193AboutSectionsView ArticleView Full TextPDF/EPUB ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareShare onFacebookTwitterLinkedInReddit View articleAbstractTweetable abstractSynthetic antiviral peptides are a promising option to overcome future viral diseases.Keywords: antiviral drugsantiviral peptidesdesign of peptidesdrug developmentmicrobial resistancesynthetic peptidesReferences1. O'Neill J. Tackling drug-resistant infections globally: final report and recommendations (2016). https://amr-review.org/sites/default/files/160525_Final%20paper_with%20cover.pdfGoogle Scholar2. CDC. 2021 Democratic Republic of the Congo, North Kivu Province. Democratic Republic of Congo. Outbreaks. Ebola (Ebola virus disease) (2021). http://www.cdc.gov/vhf/ebola/outbreaks/drc/2021-february.htmlGoogle Scholar3. CDC. About Marburg Hemorrhagic Fever. Marburg Hemorrhagic Fever (Marburg HF) (2021). http://www.cdc.gov/vhf/marburg/about.htmlGoogle Scholar4. WHO. Nipah virus outbreak in Kerala. http://www.who.int/southeastasia/outbreaks-and-emergencies/health-emergency-information-risk-assessment/surveillance-and-risk-assessment/nipah-virus-outbreak-in-keralaGoogle Scholar5. Vilas Boas LCP, Campos ML, Berlanda RLA, de Carvalho Neves N, Franco OL. Antiviral peptides as promising therapeutic drugs. Cell. Mol. Life Sci. 76(18), 3525–3542 (2019).Crossref, Medline, CAS, Google Scholar6. Souza PFN, Marques LSM, Oliveira JTA et al. Synthetic antimicrobial peptides: from choice of the best sequences to action mechanisms. Biochimie 175, 132–145 (2020).Crossref, Medline, CAS, Google Scholar7. Souza PFN, Lopes FES, Amaral JL, Freitas CDT, Oliveira JTA. A molecular docking study revealed that synthetic peptides induced conformational changes in the structure of SARS-CoV-2 spike glycoprotein, disrupting the interaction with human ACE2 receptor. Int. J. Biol. Macromol. 164, 66–76 (2020).Crossref, Medline, CAS, Google Scholar8. Souza PFN, Amaral JL, Bezerra LP et al. ACE2-derived peptides interact with the RBD domain of SARS-CoV-2 spike glycoprotein, disrupting the interaction with the human ACE2 receptor. J. Biomol. Struct. Dyn. 153, 1–14 (2021).Crossref, Google ScholarFiguresReferencesRelatedDetailsCited BySynthetic antiviral peptides: a new way to develop targeted antiviral drugsAura LC Parra, Leandro P Bezerra, Dur E Shawar, Nilton AS Neto, Felipe P Mesquita, Gabrielly O da Silva & Pedro FN Souza26 May 2022 | Future Virology, Vol. 17, No. 8Screening of isolated potential probiotic lactic acid bacteria from Sichuan pickle for cholesterol lowering property and triglycerides lowering activity1 January 2022 | Food Science and Technology, Vol. 42 Vol. 17, No. 1 Follow us on social media for the latest updates Metrics Downloaded 45 times History Received 13 August 2021 Accepted 25 October 2021 Published online 12 November 2021 Published in print January 2022 Information© 2021 Future Medicine LtdKeywordsantiviral drugsantiviral peptidesdesign of peptidesdrug developmentmicrobial resistancesynthetic peptidesFinancial & competing interests disclosureSpecial thanks to CAPES for providing the postdoctoral grant to PFN Souza. The authors have no other relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript apart from those disclosed.No writing assistance was utilized in the production of this manuscript.PDF download
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