Artigo Acesso aberto Revisado por pares

ChAdOx1 interacts with CAR and PF4 with implications for thrombosis with thrombocytopenia syndrome

2021; American Association for the Advancement of Science; Volume: 7; Issue: 49 Linguagem: Inglês

10.1126/sciadv.abl8213

ISSN

2375-2548

Autores

Alexander T. Baker, Ryan J. Boyd, Daipayan Sarkar, Alicia Teijeira, Chun Kit Chan, Emily A. Bates, Kasim Waraich, John Vant, Eric Wilson, Chloe D. Truong, Magdalena Lipka‐Lloyd, Petra Fromme, Josh V. Vermaas, Dewight Williams, LeeAnn Machiesky, Meike Heurich, Bolni Marius Nagalo, Lynda Coughlan, Scott Umlauf, Po‐Lin Chiu, P.J. Rizkallah, Taylor S. Cohen, Alan L. Parker, Abhishek Singharoy, Mitesh J. Borad,

Tópico(s)

CAR-T cell therapy research

Resumo

We observe previously unknown interactions between clinically important adenovirus vector capsids, platelet factor 4, and CAR.

Referência(s)