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Recommendations by the Scientific Department of Neuroimmunology of the Brazilian Academy of Neurology (DCNI/ABN) and the Brazilian Committee for Treatment and Research in Multiple Sclerosis and Neuroimmunological Diseases (BCTRIMS) on vaccination in general and specifically against SARS-CoV-2 for patients with demyelinating diseases of the central nervous system

2021; Thieme Medical Publishers (Germany); Volume: 79; Issue: 11 Linguagem: Inglês

10.1590/0004-282x-anp-2021-0162

1678-4227

Jéfferson Becker, Lis Campos Ferreira, Alfredo Damasceno, Denis Bernardi Bichuetti, Paulo Pereira Christo, Dagoberto Callegaro, Marco Aurélio Lana–Peixoto, Nise Alessandra de Carvalho Sousa, Sérgio Monteiro de Almeida, Tarso Adoni, Juliana Santiago-Amaral, Thiago Junqueira, Samira Luísa Apóstolos‐Pereira, Ana Beatriz Ayroza Galvão Ribeiro Gomes, Milena Sales Pitombeira, Renata Barbosa Paolilo, Anderson Kuntz Grzesiuk, Ana Cláudia Piccolo, José Arthur Costa D ́Almeida, Antônio Pereira Gomes Neto, Augusto César Penalva de Oliveira, Bianca Etelvina Santos de Oliveira, Carlos Bernardo Tauil, Claudia Ferreira Vasconcelos, Damacio Ramón Kaimen-Maciel, Daniel Varela, Denise Sisterolli Diniz, Enedina Maria Lobato de Oliveira, Fabíola Rachid Malfetano, Fernando Elias Borges, Fernando Faria Andrade Figueira, Francisco de Assis Aquino Gondim, Giordani Rodrigues dos Passos, Guilherme Diogo Silva, Guilherme Sciascia do Olival, Gutemberg Augusto Cruz dos Santos, Heloísa Helena Ruocco, Henry Koiti Sato, Herval Ribeiro Soares Neto, Leandro Cortoni Calia, Marcus Vinícius Magno Gonçalves, Maria Cecília Aragon de Vecino, Maria Lúcia Vellutini Pimentel, Marlise de Castro Ribeiro, Mateus Boaventura de Oliveira, Mônica Koncke Fiuza Parolin, Renata Brant de Souza Melo, Robson Lázaro, Rodrigo Barbosa Thomaz, Rodrigo Kleinpaul, Ronaldo Maciel Dias, Sidney Gomes, Simone Abrante Lucatto, Soniza Vieira Alves‐Leon, Thiago Gonçalves Fukuda, T.A.G.J. Ribeiro, Thereza Cristina d’Ávila Winckler, Yára Dadalti Fragoso, Osvaldo J. M. Nascimento, Maria Lúcia Brito Ferreira, María Fernanda Mendes, Doralina Guimarães Brum, Felipe von Glehn,

Peripheral Neuropathies and Disorders

The Scientific Department of Neuroimmunology of the Brazilian Academy of Neurology (DCNI/ABN) and Brazilian Committee for Treatment and Research in Multiple Sclerosis and Neuroimmunological Diseases (BCTRIMS) provide recommendations in this document for vaccination of the population with demyelinating diseases of the central nervous system (CNS) against infections in general and against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which causes COVID-19. We emphasize the seriousness of the current situation in view of the spread of COVID-19 in our country. Therefore, reference guides on vaccination for clinicians, patients, and public health authorities are particularly important to prevent some infectious diseases. The DCNI/ABN and BCTRIMS recommend that patients with CNS demyelinating diseases (e.g., MS and NMOSD) be continually monitored for updates to their vaccination schedule, especially at the beginning or before a change in treatment with a disease modifying drug (DMD). It is also important to note that vaccines are safe, and physicians should encourage their use in all patients. Clearly, special care should be taken when live attenuated viruses are involved. Finally, it is important for physicians to verify which DMD the patient is receiving and when the last dose was taken, as each drug may affect the induction of immune response differently.