Identification of miRNA Changes in Alzheimer's Disease Brain and CSF Yields Putative Biomarkers and Insights into Disease Pathways
2008; IOS Press; Volume: 14; Issue: 1 Linguagem: Inglês
10.3233/jad-2008-14103
ISSN1875-8908
AutoresJohn Cogswell, James M. Ward, Ian A. Taylor, Michelle Waters, Yunling Shi, Brian D. Cannon, Kevin Kelnar, Jon Kemppainen, David Brown, Caifu Chen, Rab K. Prinjha, Jill Richardson, Ann M. Saunders, Allen D. Roses, Cynthia A. Richards,
Tópico(s)RNA regulation and disease
ResumoMicroRNAs have essential functional roles in brain development and neuronal specification but their roles in neurodegenerative diseases such as Alzheimer's disease (AD) is unknown. Using a sensitive qRT-PCR platform we identified regional and stage-s
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