Standardized Echography, Pattern Electroretinography and Visual-Evoked Potential and Automated Perimetry in the Early Diagnosis of Graves’ Neuropathy
1998; Karger Publishers; Volume: 212; Issue: Suppl. 1 Linguagem: Inglês
10.1159/000055442
ISSN1423-0267
AutoresFederica Genovesi-Ebert, Emanuele Di Bartolo, Antonio Lepri, Vincenzo Poggi, Andrea Romani, Marco Nardi,
Tópico(s)Drug-Induced Ocular Toxicity
ResumoTwenty-four patients (47 eyes) affected by Graves’ disease were enrolled to evaluate the role of standardized echography, pattern electroretinogram (P-ERG), visual evoked potentials (P-VEPs) and automated perimetry in the early diagnosis of the compressive optic neuropathy (CON). The P-ERG amplitude reduction was the most sensitive parameter to demonstrate an early impairment of the optic nerve (ON) function. We found a significant negative correlation between the ON diameter and the P-ERG amplitude. VEPs responses were also altered, but their ability in detecting an early ON damage was less sensitive and specific than P-ERG. The visual field damage was often aspecific and delayed with respect to electrophysiological alterations.
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