COMMENTARY
2001; Elsevier BV; Volume: 17; Issue: 4 Linguagem: Inglês
10.1016/s0749-0704(05)70192-5
ISSN1557-8232
AutoresGilbert Park, Douglas B. Coursin, E. Wesley Ely, Michael R. England, Gilles L. Fraser, Jean Mantz, Sharon McKinley, Michael A. E. Ramsay, Jens Scholz, Mervyn Singer, Robert N. Sladen, Jeffery S. Vender, Lorie Wild,
Tópico(s)Cardiac, Anesthesia and Surgical Outcomes
ResumoSedatives and analgesics are administered to upwards of 92% of critically ill patients in the United States 9 Dasta J.F. Fuhrman T.M. McCandles C. Patterns of prescribing and administering drugs for agitation and pain in patients in a surgical intensive care unit. Crit Care Med. 1994; 22: 974-980 Crossref PubMed Scopus (87) Google Scholar at an estimated annual cost of 8 million to 1.2 billion dollars. 25 Kress J.P. Pohlman A.S. O'Connor M.F. et al. Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation. N Engl J Med. 2000; 342: 1471-1477 Crossref PubMed Scopus (2244) Google Scholar The drugs are easy to administer, but avoiding over- and undersedation is challenging. Maintenance of a target level of sedation is difficult; patients spend a significant proportion of their ICU stay at inappropriate levels of sedation. 34 Ostermann M.E. Keenan S.P. Seiferling R.A. et al. Sedation in the intensive care unit: A systematic review. JAMA. 2000; 283: 1451-1459 Crossref PubMed Scopus (329) Google Scholar
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