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Angiotensins I and II, active and inactive renin, renin substrate, renin activity, and angiotensinase in human liquor amnii and plasma

1975; Elsevier BV; Volume: 121; Issue: 5 Linguagem: Inglês

10.1016/0002-9378(75)90463-9

1097-6868

Sandford L. Skinner, E. Cran, Robyn Gibson, Renea A. Taylor, W.A.W. Walters, Kevin Catt,

Renin-Angiotensin System Studies

Abstract Most of the renin in liquor amnii and plasma exists in an inactive form which can be activated by acidification to pH 3.3. In liquor collected by paracentesis at 34 to 37 weeks' gestation, 83 per cent of renin was inactive (n = 37). This proportion was unrelated to the total amount present. In first trimester plasma, the proportion inactive (73 per cent) was greater than in term plasma (65 per cent, P