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The Chemistry of Tryptophan in Peptides and Proteins

1976; Springer Science+Business Media; Linguagem: Inglês

10.1007/978-3-7091-3262-3_4

2192-4309

Angelo Fontana, Claudio Toniolo,

Chemical Synthesis and Analysis

The chemistry of tryptophan (1) has probably been the object of more intense investigation than that of any other amino acids. This is undoubtedly due to the particular reactivity of the indole nucleus and to the extensive chemistry developed over the years regarding this important and ubiquitous functionality. Only the sulfur amino acids have received comparable attention from chemists and biochemists.