Portal de Periódicos da CAPES

Possible synergism between fluoxetine and lithium in refractory depression

1988; American Psychiatric Association; Volume: 145; Issue: 10 Linguagem: Inglês

10.1176/ajp.145.10.1292

1535-7228

H G Pope, S L McElroy, Ralph A. Nixon,

Bipolar Disorder and Treatment

Five depressed patients who had shown no improvement with trials of antidepressants from several chemical families, including fluoxetine, responded when lithium was given in conjunction with fluoxetine. Lithium augmentation of fluoxetine may represent a useful strategy in refractory depression.