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Thyroid Hormone Synthesis, Plasma Membrane Transport and Metabolism

1997; Springer Science+Business Media; Linguagem: Inglês

10.1007/978-3-642-60709-7_4

1865-0325

G Hennemann, T.J. Visser,

Birth, Development, and Health

The most important iodothyronine secreted by the thyroid gland is 3,5,3',5'-tetraiodothyronine (thyroxine, T4). Thyroxine has little, if any, biological activity, and is converted to the active hormone par excellence, i.e. 3,5,3'-triiodothyronine (T3). In man about 80% of total plasma T3 production is extrathyroidally converted to T3 (see below), while 20% is secreted by the thyroid gland.